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Protagonist Therapeutics logo
Protagonist Therapeutics PTGX
$ 128.75 0.2%
report update icon

Quarterly report 2026-Q2
added 08-05-2026

Protagonist Therapeutics Financial Ratios 2025-2011 | PTGX

Brief overview of Protagonist Therapeutics's valuation multiples

The comparison uses the five latest available annual observations between 2021 and 2025.

The latest available valuation ratios are P/S 120.21x (median 44.48x), P/B 9x (median 5x), P/CF 95.91x (median 95.91x). Valuation is 80.1% above five-year reference levels. The premium requires support from earnings and returns.

End-period return metrics are ROE -21.2%, ROA -19.5%, ROCE -25.7%. Losses and negative capital returns make ordinary P/E-like references unstable or inapplicable.

On PEG (0.42x), valuation is restrained relative to growth, but one ratio cannot replace cash-flow and risk analysis.

Valuation takeaway

Protagonist Therapeutics's profile looks stretched: price anticipates improvement that current quality ratios do not yet confirm.

Annual Financial Ratios Protagonist Therapeutics

2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

P/E

-42.5 8.7 -21.3 -9.3 -10.8 -10.8 -2.5 -4.6 -10.5 -3.3 - - - - -

P/S

120.2 5.5 28.0 44.5 49.6 24.9 822.8 5.9 19.4 - - - - - -

EPS

-2.0 4.5 -1.4 -2.6 -2.7 -1.9 -3.0 -1.7 -2.1 -5.8 -59.3 -49.4 - - -

EV (Enterprise Value)

5.46 B 2.37 B 1.52 B 1.09 B 1.28 B 640 M 232 M 126 M 326 M 108 M 1.19 M 2.37 M - - -

EBITDA per Share

-2.47 4.12 -1.63 -2.66 -2.7 -1.85 -3.01 -1.87 -2.12 -4.98 - - - - -

EV/EBITDA

-34.8 9.4 -16.4 -8.4 -10.1 -10.7 -2.1 -2.4 -7.5 -3.1 - - - - -

PEG

0.42 -0.11 -3.73 -0.84 100.33 -0.33 0.03 -0.28 -0.16 0.05 - - - - -

P/B

9.0 3.6 5.0 5.5 4.5 2.5 2.4 1.6 3.2 1.4 - - - - -

P/CF

95.9 13.0 -23.9 -10.9 -12.6 -9.8 -4.5 -3.6 121.2 -4.0 - - - - -

ROE %

-21.17 40.75 -23.45 -59.09 -41.85 -23.66 -96.53 -34.59 -30.64 -42.46 - - - - -

ROA %

-19.48 36.95 -22.06 -51.38 -36.11 -20.39 -49.82 -27.91 -22.57 -39.55 - - - - -

ROCE %

-25.72 37.44 -27.82 -60.93 -41.95 -23.07 -67.38 -37.30 -31.27 -37.31 - - - - -

Current Ratio

12.5 10.7 16.8 7.7 7.3 7.2 4.1 5.3 3.5 12.9 - - - - -

DSO

- - - - - - 10673.5 71.0 57.5 - - - - - -

All numbers in USD currency

Quarterly Financial Ratios Protagonist Therapeutics

2026-Q2 2026-Q1 2025-Q4 2025-Q3 2025-Q2 2025-Q1 2024-Q4 2024-Q3 2024-Q2 2024-Q1 2023-Q4 2023-Q3 2023-Q2 2023-Q1 2022-Q4 2022-Q3 2022-Q2 2022-Q1 2021-Q4 2021-Q3 2021-Q2 2021-Q1 2020-Q4 2020-Q3 2020-Q2 2020-Q1 2019-Q4 2019-Q3 2019-Q2 2019-Q1 2018-Q4 2018-Q3 2018-Q2 2018-Q1 2017-Q4 2017-Q3 2017-Q2 2017-Q1 2016-Q4 2016-Q3 2016-Q2 2016-Q1 2015-Q4 2015-Q3 2015-Q2 2015-Q1 2014-Q4 2014-Q3 2014-Q2 2014-Q1 2013-Q4 2013-Q3 2013-Q2 2013-Q1 2012-Q4 2012-Q3 2012-Q2 2012-Q1 2011-Q4 2011-Q3 2011-Q2 2011-Q1

EPS

2.47 0.06 - -0.62 -0.55 -0.19 - -0.54 -0.5 3.41 - -0.58 -0.68 -0.67 - -0.64 -0.84 -0.43 - -0.7 -0.69 -0.54 - -0.21 -0.59 -0.72 -0.63 -0.61 -1.18 -0.58 -0.57 -0.38 -0.41 -0.36 -0.15 -0.29 -0.89 -0.84 -0.67 -0.87 -19.07 -40.96 -20.31 -12.79 -13.78 -11.75 - - - - - - - - - - - - - - - -

EBITDA per Share

2.42 -0.05 - - - -0.3 - - - 3.39 - - - -0.71 - -0.64 -0.84 -0.43 - -0.69 -0.69 -0.54 - -0.19 -0.54 -0.7 -0.64 -0.62 -1.26 -0.6 -0.66 -0.39 -0.42 -0.39 -0.17 -0.28 -0.89 -0.85 -0.68 -0.81 -18.1 -24.2 -18.4 -14.2 -12.7 - - - - - - - - - - - - - - - - -

ROE %

8.63 -12.41 -12.99 -19.23 -18.80 23.40 25.10 13.81 6.97 -2.97 -39.97 -52.79 -56.81 -50.67 -35.07 -45.32 -41.13 -35.07 -28.14 -30.91 -27.60 -26.16 -16.90 -38.79 -56.53 -86.07 -96.53 -86.96 -74.21 -45.42 -34.59 -24.80 -21.04 -25.76 -30.64 -40.95 -45.04 -40.73 -42.46 -9.57 11.11 30.97 20.05 12.59 11.75 - - - - - - - - - - - - - - - - -

ROA %

8.48 -11.48 -12.02 -17.52 -16.89 20.90 22.47 12.13 5.63 -3.45 -36.40 -47.46 -43.14 -40.20 -26.14 -33.77 -22.70 -30.75 -24.74 -27.13 -24.06 -22.62 -14.57 -25.86 -34.06 -46.91 -49.82 -48.47 -44.14 -31.52 -27.91 -19.83 -16.51 -19.45 -22.57 -32.67 -37.26 -35.67 -39.55 -64.59 -80.29 -94.42 -37.00 -23.23 -21.68 - - - - - - - - - - - - - - - - -

ROCE %

4.82 -16.84 -16.29 -24.08 -24.06 19.05 21.85 9.17 2.56 -6.94 -43.75 -57.01 -59.79 -52.38 -35.72 -46.01 -41.39 -35.19 -28.19 -30.97 -27.20 -25.60 -16.34 -37.97 -56.66 -89.42 -100.70 -92.76 -79.64 -48.57 -37.57 -26.78 -22.57 -26.90 -31.42 -41.52 -45.54 -41.10 -37.31 -6.04 16.79 36.14 18.25 14.68 11.25 - - - - - - - - - - - - - - - - -

Current Ratio

20.1 16.6 12.5 12.5 14.4 14.0 10.7 8.4 8.4 9.1 16.8 11.8 12.1 10.1 7.7 7.3 - 7.5 7.3 8.6 8.6 7.7 7.2 7.2 7.2 7.2 2.1 2.1 2.1 2.1 5.2 5.2 5.2 5.2 3.8 3.8 3.8 3.8 14.6 14.6 14.6 - 2.8 2.8 2.8 - - - - - - - - - - - - - - - - -

All numbers in USD currency

Multiples are an important financial analysis tool for the company Protagonist Therapeutics, allowing investors and analysts to quickly assess the company’s value and investment attractiveness based on the ratio of market indicators to the company’s financial performance. Essentially, multiples express how the market values the company relative to its earnings, revenue, equity, or other key metrics.

Advantages of Using Financial Ratios
  • Simplified Data Analysis
    Financial ratios transform large volumes of accounting data into compact and easily interpretable indicators, significantly simplifying the assessment of the company’s condition.
  • Comparability Between Companies
    Multiples standardize financial metrics, enabling objective comparison of companies of different sizes, industries, and market capitalizations.
  • Identification of Trends and Issues
    Regular analysis of ratios helps track the dynamics of financial health, identify strengths and weaknesses of the business, as well as potential risks.
  • Decision Support
    Financial multiples serve as an important tool for investors, creditors, and company management in making investment, credit, and managerial decisions.
  • Accelerated Assessment of Investment Attractiveness
    Ratios allow quick determination of key performance, liquidity, and financial stability indicators, facilitating prompt evaluation of companies’ attractiveness for investments.

Using multiples enables comparison between companies, even if they differ in size or industry, as they standardize financial data into ratios convenient for analysis. This is especially useful for evaluating companies where direct analysis of financial statements may be complex or require in-depth knowledge.

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