Spero Therapeutics logo
Spero Therapeutics SPRO
$ 1.16 4.13%
report update icon

Quarterly report 2026-Q2
added 08-12-2026

Spero Therapeutics Financial Ratios 2025-2011 | SPRO

Brief overview of Spero Therapeutics's financial ratios

The review covers five available annual periods spanning 2021 to 2025.

Key multiples at the end of the period are EV/EBITDA 16.22x (median 2.65x), P/S 1.99x (median 1.99x), P/B 2.25x (median 2.25x). The combined ratio level is close to the company's five-year norm at a 0% deviation. No clear premium or discount is visible.

Capital efficiency is characterized by ROE 14.5%, ROA 12.4%, ROCE 10.7%. Capital returns look adequate and support overall financial resilience.

Overall picture

Spero Therapeutics trades near its familiar ratio range. A new earnings or profitability trend is needed to change the view.

Annual Financial Ratios Spero Therapeutics

2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

P/E

15.5 -1.9 3.8 -1.1 -4.1 -4.2 -2.9 -3.7 -0.8 - -4.9 - - - -

P/S

2.0 2.7 0.8 1.0 20.1 35.3 9.7 38.4 16.2 - - - - - -

EPS

0.1 -1.3 0.4 -1.2 -2.9 -3.5 -3.4 -2.6 -17.8 -95.9 -53.1 - - - -

EV (Enterprise Value)

102 M 140 M 86.7 M -7.24 M 337 M 265 M 178 M 131 M -46.7 M 7.41 M 56.9 M - - - -

EBITDA per Share

0.11 -1.36 0.41 -1.1 -2.83 -4.31 -3.44 -2.65 -16 - -0.971 - - - -

EV/EBITDA

16.2 -1.9 4.0 0.2 -3.6 -3.1 -2.3 -2.8 1.3 - -4.4 - - - -

PEG

-0.1 0.01 -0.11 0.05 - 0.15 0.1 -0.04 0.01 - 1.63 - - - -

P/B

2.2 2.8 0.8 0.7 4.2 2.5 2.4 1.3 0.4 - 252.4 - - - -

P/CF

-10.5 -5.5 -2.7 -6.9 -5.7 -3.8 -3.5 -3.6 -0.8 - -5.0 - - - -

ROE %

14.52 -148.66 21.34 -61.13 -101.66 -59.29 -81.70 -36.07 -45.79 - -5180.61 - - - -

ROA %

12.44 -62.03 12.50 -37.19 -52.47 -51.01 -57.42 -32.29 -41.45 - -141.50 - - - -

ROCE %

10.70 -159.06 20.10 -55.57 -99.64 -56.87 -79.58 -36.68 -48.91 - -1742.12 - - - -

Current Ratio

7.0 1.7 2.4 2.6 2.1 9.7 3.6 10.1 11.3 - 0.9 - - - -

DSO

- - - - - 241.6 171.9 119.5 542.8 - - - - - -

All numbers in USD currency

Quarterly Financial Ratios Spero Therapeutics

2026-Q2 2026-Q1 2025-Q4 2025-Q3 2025-Q2 2025-Q1 2024-Q4 2024-Q3 2024-Q2 2024-Q1 2023-Q4 2023-Q3 2023-Q2 2023-Q1 2022-Q4 2022-Q3 2022-Q2 2022-Q1 2021-Q4 2021-Q3 2021-Q2 2021-Q1 2020-Q4 2020-Q3 2020-Q2 2020-Q1 2019-Q4 2019-Q3 2019-Q2 2019-Q1 2018-Q4 2018-Q3 2018-Q2 2018-Q1 2017-Q4 2017-Q3 2017-Q2 2017-Q1 2016-Q4 2016-Q3 2016-Q2 2016-Q1 2015-Q4 2015-Q3 2015-Q2 2015-Q1 2014-Q4 2014-Q3 2014-Q2 2014-Q1 2013-Q4 2013-Q3 2013-Q2 2013-Q1 2012-Q4 2012-Q3 2012-Q2 2012-Q1 2011-Q4 2011-Q3 2011-Q2 2011-Q1

EPS

-0.03 -0.13 - -0.13 -0.03 -0.25 - -0.32 -0.33 -0.24 - -0.06 -0.23 -0.25 - -0.33 -0.87 -1.01 - -0.7 -0.63 -0.66 - -0.86 -0.85 -1.22 -1.31 -0.95 -0.74 -0.29 -0.6 -0.6 -0.69 -0.74 -1.59 -36.02 -36.21 -21.6 -25.68 -23.23 -25.3 -21.51 - - - - - - - - - - - - - - - - - - - -

EBITDA per Share

-0.04 -0.13 - - - - - - - - - - - -0.27 - -0.31 -0.78 -0.92 - -0.69 -0.61 -0.65 - -0.84 -0.88 -1.16 - -0.92 -0.75 -0.32 - -0.61 -0.68 -0.75 - -28.9 -29.9 -22.8 - -24.2 - - - - - - - - - - - - - - - - - - - - - -

ROE %

-50.33 -87.66 -74.05 -100.22 -94.55 -102.53 -61.53 -67.50 -63.04 -61.37 -48.20 -84.22 -158.15 -188.93 -168.41 -188.52 -173.11 -109.54 -57.04 -71.35 -64.50 -61.54 -45.21 -78.72 -88.14 -92.59 -81.78 -57.45 -42.77 -33.69 -36.07 -43.28 -79.96 -117.09 -153.62 -121.36 -61.72 -45.74 15.87 13.90 - - - - - - - - - - - - - - - - - - - - - -

ROA %

-31.03 -46.41 -34.21 -46.89 -45.18 -50.00 -32.16 -35.15 -34.50 -34.40 -26.84 -44.99 -87.10 -97.56 -85.74 -101.29 -98.70 -67.12 -44.63 -56.94 -52.80 -52.43 -38.90 -62.45 -66.82 -67.86 -57.48 -42.15 -33.57 -28.85 -32.29 -38.91 -72.20 -105.88 -139.03 -176.56 -181.02 -41.40 -52.36 -45.86 - - - - - - - - - - - - - - - - - - - - - -

ROCE %

-56.86 -95.13 -80.89 -109.27 -103.07 -110.15 -66.59 -70.19 -65.34 -63.60 -49.07 -85.50 -154.50 -179.32 -157.38 -177.51 -161.63 -105.35 -57.00 -71.41 -65.27 -62.01 -45.68 -69.80 -73.70 -67.35 -50.06 -59.53 -44.05 -35.10 -27.46 -39.24 -41.79 -42.14 -32.78 -15.36 -12.02 -8.98 - 17.42 - - - - - - - - - - - - - - - - - - - - - -

Current Ratio

7.0 9.7 1.7 2.0 2.1 1.8 1.7 1.9 2.2 2.4 2.4 2.0 2.2 2.4 2.5 2.0 2.3 1.8 2.1 4.4 4.1 5.8 7.2 7.2 7.2 7.2 3.4 3.4 3.4 3.4 9.8 9.8 9.8 9.8 11.0 11.0 11.0 11.0 1.9 1.9 - - - - - - - - - - - - - - - - - - - - - -

All numbers in USD currency

Multiples are an important financial analysis tool for the company Spero Therapeutics, allowing investors and analysts to quickly assess the company’s value and investment attractiveness based on the ratio of market indicators to the company’s financial performance. Essentially, multiples express how the market values the company relative to its earnings, revenue, equity, or other key metrics.

Advantages of Using Financial Ratios
  • Simplified Data Analysis
    Financial ratios transform large volumes of accounting data into compact and easily interpretable indicators, significantly simplifying the assessment of the company’s condition.
  • Comparability Between Companies
    Multiples standardize financial metrics, enabling objective comparison of companies of different sizes, industries, and market capitalizations.
  • Identification of Trends and Issues
    Regular analysis of ratios helps track the dynamics of financial health, identify strengths and weaknesses of the business, as well as potential risks.
  • Decision Support
    Financial multiples serve as an important tool for investors, creditors, and company management in making investment, credit, and managerial decisions.
  • Accelerated Assessment of Investment Attractiveness
    Ratios allow quick determination of key performance, liquidity, and financial stability indicators, facilitating prompt evaluation of companies’ attractiveness for investments.

Using multiples enables comparison between companies, even if they differ in size or industry, as they standardize financial data into ratios convenient for analysis. This is especially useful for evaluating companies where direct analysis of financial statements may be complex or require in-depth knowledge.

Financial Ratios of other stocks in the Biotechnology industry

Issuer Price % 24h Market Cap Country
Институт стволовых клеток человека Институт стволовых клеток человека
ISKJ
- - - russiaRussia
ММЦБ ММЦБ
GEMA
- - - russiaRussia
Lyra Therapeutics Lyra Therapeutics
LYRA
- - $ 24.9 M usaUSA
Завод ДИОД Завод ДИОД
DIOD
- - - russiaRussia
Фармсинтез Фармсинтез
LIFE
- - - russiaRussia
ОЗОН Фармацевтика ОЗОН Фармацевтика
OZPH
- - - russiaRussia
Промомед Промомед
PRMD
- - - russiaRussia
Ionis Pharmaceuticals Ionis Pharmaceuticals
IONS
$ 43.5 0.62 % $ 6.96 B usaUSA
Agios Pharmaceuticals Agios Pharmaceuticals
AGIO
$ 31.25 0.88 % $ 1.81 B usaUSA
Foghorn Therapeutics Foghorn Therapeutics
FHTX
$ 2.0 0.74 % $ 126 M usaUSA
Inhibikase Therapeutics Inhibikase Therapeutics
IKT
$ 2.0 0.5 % $ 197 M usaUSA
Kamada Ltd. Kamada Ltd.
KMDA
$ 8.0 1.34 % $ 461 M israelIsrael
Intellia Therapeutics Intellia Therapeutics
NTLA
$ 12.75 4.0 % $ 1.38 B usaUSA
Ultragenyx Pharmaceutical Ultragenyx Pharmaceutical
RARE
$ 14.5 3.19 % $ 1.43 B usaUSA
Viridian Therapeutics Viridian Therapeutics
VRDN
$ 19.0 2.16 % $ 1.93 B usaUSA
AbbVie AbbVie
ABBV
$ 265.76 1.12 % $ 470 B usaUSA
AbCellera Biologics AbCellera Biologics
ABCL
$ 13.78 0.29 % $ 4.12 B canadaCanada
Abeona Therapeutics Abeona Therapeutics
ABEO
$ 5.11 1.59 % $ 271 M usaUSA
Arbutus Biopharma Corporation Arbutus Biopharma Corporation
ABUS
$ 4.67 4.94 % $ 895 M canadaCanada
ACADIA Pharmaceuticals ACADIA Pharmaceuticals
ACAD
$ 20.11 0.8 % $ 3.39 B usaUSA
Achieve Life Sciences Achieve Life Sciences
ACHV
$ 7.01 0.13 % $ 306 M usaUSA
AC Immune SA AC Immune SA
ACIU
$ 2.71 0.55 % $ 273 M schweizSchweiz
Aclaris Therapeutics Aclaris Therapeutics
ACRS
$ 4.27 0.79 % $ 523 M usaUSA
Adagene Adagene
ADAG
$ 2.8 0.28 % $ 165 M chinaChina
ADC Therapeutics SA ADC Therapeutics SA
ADCT
$ 1.23 8.85 % $ 156 M schweizSchweiz
Adial Pharmaceuticals Adial Pharmaceuticals
ADIL
$ 4.35 5.58 % $ 2.91 M usaUSA
ADMA Biologics ADMA Biologics
ADMA
$ 10.11 4.01 % $ 2.41 B usaUSA
Adaptive Biotechnologies Corporation Adaptive Biotechnologies Corporation
ADPT
$ 29.84 5.26 % $ 4.53 B usaUSA
Agenus Agenus
AGEN
$ 8.73 4.43 % $ 260 M usaUSA
AIM ImmunoTech AIM ImmunoTech
AIM
$ 0.19 5.56 % $ 308 K usaUSA
Akebia Therapeutics Akebia Therapeutics
AKBA
$ 0.91 5.26 % $ 234 M usaUSA
Akari Therapeutics, Plc Akari Therapeutics, Plc
AKTX
$ 8.76 0.46 % $ 590 B britainBritain
Aldeyra Therapeutics Aldeyra Therapeutics
ALDX
$ 0.92 4.88 % $ 55.3 M usaUSA
Alector Alector
ALEC
$ 1.99 9.94 % $ 205 M usaUSA
Aligos Therapeutics Aligos Therapeutics
ALGS
$ 5.4 0.36 % $ 53.4 M usaUSA
Alkermes plc Alkermes plc
ALKS
$ 42.76 2.42 % $ 7.04 B irlandaIrlanda
Allogene Therapeutics Allogene Therapeutics
ALLO
$ 1.5 0.33 % $ 331 M usaUSA
Alnylam Pharmaceuticals Alnylam Pharmaceuticals
ALNY
$ 219.89 0.08 % $ 28.8 B usaUSA
Altimmune Altimmune
ALT
$ 2.67 0.36 % $ 235 M usaUSA
ALX Oncology Holdings ALX Oncology Holdings
ALXO
$ 1.21 1.23 % $ 64.9 M usaUSA
Amgen Amgen
AMGN
$ 402.98 0.08 % $ 217 B usaUSA
Amphastar Pharmaceuticals Amphastar Pharmaceuticals
AMPH
$ 25.37 0.39 % $ 1.19 B usaUSA
Amarin Corporation plc Amarin Corporation plc
AMRN
$ 12.09 0.31 % $ 5.02 B irlandaIrlanda
Amneal Pharmaceuticals Amneal Pharmaceuticals
AMRX
$ 20.35 0.25 % $ 6.38 B usaUSA
AnaptysBio AnaptysBio
ANAB
$ 49.2 1.38 % $ 1.43 B usaUSA
Anika Therapeutics Anika Therapeutics
ANIK
$ 19.73 3.3 % $ 283 M usaUSA
ANI Pharmaceuticals ANI Pharmaceuticals
ANIP
$ 72.58 0.55 % $ 1.46 B usaUSA
Annexon Annexon
ANNX
$ 4.2 0.24 % $ 651 M usaUSA
Annovis Bio Annovis Bio
ANVS
$ 1.2 1.69 % $ 24.7 M usaUSA
Aprea Therapeutics Aprea Therapeutics
APRE
$ 0.68 0.16 % $ 4.45 M usaUSA